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Fig. 2: Fluid-flow shear stress (ffss) regulates sost expression through HDAC4/5 nuclear translocation and changes in FAK/integrin signaling. Fig. 3: FAK is required for FFSS-induced gene …

Cannabidiol (CBD) was first isolated from Minnesota wild hemp in 1940. It was not until 1963 that the exact structure was discovered by Raphael Mechoulam, the father of cannabis research.

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